Polyparasitism with malaria and intestinal parasite infections in febrile children attending General Hospital Bayara, Bauchi State, Nigeria

Mukhtar Adamu Muhammad, Samail Abayo Adamu, Yusuf Yahya Miya, Ruqayyah Hamidu Muhammad, Ikilimatu Ibrahum Tanko, Jamil Hassan Abdulkareem

Abstract


Background: This work was intended to detect prevalence of polyparasitism with malaria and of intestinal parasite infections in febrile children, as well as to determine the prevalence of Polyparasitism with malaria and of intestinal parasite infections in febrile children aged between 1-10 years attending General Hospital Bayara Bauchi state.

Materials and methods: A cross-sectional study of febrile children admitted at General Hospital Bayara between February and October 2023 was conducted. Fresh stool and blood samples were collected, thin and thick blood film were performed using Giemsa-stained and blood film was examined for malaria parasites, while wet mount smear and zinc floatation method was done intestinal parasites infections (IPIs). The Pearson’s chi-square and multivariate analysis (MANOVA) were all carried out.

Results: Six hundred and sixty-six (666) children successfully took part in this study. The overall prevalence of malaria and polyparasitism observed were 76.3%. 57.3% were found to be infected with Plasmodium falciparum specie of Malaria parasite, while polyparasites of intestinal parasites found were Ancylostoma duodenale accounting for 22.4%; 15.6% for Ascaris lumbricoides; Entamoeba histolytica 3.3%; Giardia lamblia 1.0% and Taenia specie were the least Polyparasitism accounting for 0.4%. A significant association between Malaria and Not regularly used of (LLIN) (p = 0.002) which was observed at (confidence interval of 0.01). There was no significant association in the prevalence of polyparasitism with communities of children infected with malaria (p=0.340). Conclusion: This study showed that malaria and IPIs still constitute a major public health problem in the study area despite a lack of any significant association between these infections and communities. The findings suggest that there is a need for the implementation of control measures to curb the rate of malaria and IPIs in the study area.

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References


Adeniran A. A, H. O. Mogaji, A. A. Aladesida et al., 2017 “Schisto- somiasis, intestinal helminthiasis and nutritional status among preschool-aged children in sub-urban communities of Abeo- kuta, Southwest, Nigeria,” BMC Research Notes, 10, ( 1):1-37.

Albonico M, H. Allen, L. Chitsulo, D. Engels, A. F. Gab-rielli, and L. Savioli, “Controlling soil-transmitted helmin- thiasis in pre-school-age children through preventive chemotherapy,”PLoS Neglected Tropical Diseases, 2 (3):126,2008.

Alemu A, Shiferaw Y, Ambachew A, and Hamid H (2012). Malaria helminth co-infections and their contribution for anaemia in febrile patients attending Azzezo health center, Gondar, Northwest Ethiopia: a cross sectional study. Asian Pacific Journal of Tropical Medicine. 5:803–9.

Bethony J, S. Brooker, M. Albonico et al., (2006). “Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm,” Lancet, 367(9521):1521–1532, 2006.

Booth M, Vennervald BJ, Kabatereine NB, Kazibwe F, Ouma JH, Kariuki CH, et al. (2004). Hepatosplenic morbidity in two neighbouring communities in Uganda with high levels of schistosoma mansoni infection but very different durations of residence. Trans Roy Soc Trop Med Hyg.98:125–36.

Brooker S, B. Estambale, R. Pullan et al., (2007). “Epidemiology of plasmodium-helminth co-infection in Africa: populations at risk, potential impact on anemia, and prospects for combining control,” American Journal of Tropical Medicine and Hygiene, 77, 6_Supplement, pp. 88–98.

Center for Disease Control and Prevention, Malaria World- wide, 2014, July 2015 http://www.cdc.gov/malaria/malaria_worldwide/index.html.

Cheesbrough M. (2006). District Laboratory Practice in Tropical Countries. Seconds ed. Cambridge: Cambridge University Press.pp. 178235.

Cheesbrough M. (2009). District laboratory practice in tropical countries. Cambridge: Cambridge University Press: Part1&2.

Chi, H. F., Nkuo-Akenji, T. (2016). Malaria, helminths, co-infection and anaemia in a cohort of children from Mutengene, south western Cameroon. Malaria Journal, 15(1), 69. https://doi.org/10.1186/s12936-016-1111-2.

Commission (NPopC), National Bureau of Statistics (NBS), ICF International. Nigeria Malaria Indicator Survey 2015, Abuja, Nigeria, and Rockville, Maryland, USA; 2016 (cited 2021 Feb 27).

Coulibaly J.T., Knopp S, N'Guessan N.A., Silué K.D., Fürst T, Lohourignon L.K., Brou J.K., Brou J.K, N'Gbesso YK, Vounatsou P, N'Goran EK, et al: (2011). Accuracy of urine circulating cathodic antigen (CCA) test for Schistosoma mansoni diagnosis in different settings of Côte d'Ivoire. PLoS Negl Trop Dis; 2011, 5: e1384.10.

Datoo MS, Natama MH, Somé A, Traoré O, Rouamba T, Bellamy D, et al. (May 2021). Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial". Lancet. 397 (10287): 1809–1818. doi:10.1016/S0140-6736(21)00943-0. PMC 8121760. PMID 33964223. SSRN 3830681.

Degarege A, Legesse M, Medhin G, Animut A. and Erko B. (2012). Malaria and related outcomes in patients with intestinal helminths: a cross-sectional study. BMC Infect Dis. (2012) 12:291. 10.1186/1471-2334-12-291

Florey L. S, (2009). Epidemiology of polyparasitism in coastal Kenya: determinants, interactions and health effects of plasmodium species and Schistosoma haematobium infections. Case Western Reserve University.

Friedman J. F, H. K. Kanzaria, and S. T. McGarvey, (2005). “Human Schistosomiasis and anemia: the relationship and potential mechanisms,” TrendsinParasitology, vol. 21, (8): 386– 392.

Garba,S., Dikko, M., Bala, B.I., Malami, Z. and Sarkingobir, Y. (2024a). Surveyed Determinants of rotavirus among diarrheal children 90-5yrs) attending some health facilities in Sokoto Town, Nigeria. Kashmir Journal of Science, 3(1): 55-67.

Garba,S., Dikko, M., Bala, B.I., Malami, Z. and Sarkingobir, Y. (2024b). Laconically reviewed concepts pertaining the rotavirus: A severe diarrhea causing microbe. Thu Dau Maut University Journal of Science, 6(1): 1-36.

Hürlimann E, R. B. Yapi, C. A. Houngbedji et al., (2014). “The epidemiology of polyparasitism and implications for morbidity in two rural communities of Côte d’Ivoire,” Parasites & Vectors’’ 7(1): 69-81.

Kinung’hi S.M, Magnussen P, Kaatano G.M, Kishamawe C, Vennervald B.J. et al. (2014). Malaria and Helminth Co-Infections in School and Preschool Children: A Cross-Sectional Study in Magu District, North-Western Tanzania. PLoS ONE.9(1): e86510.

Larson, P.N., Bjorgen, S.D. and Wongraven, M.C. (2017). Prevalence of malaria and soil transmitted helminth infections in healthy school children in Cameroon. International Journal of Malaria and Tropical Diseases,1(7):30-37.

Matanglia, J.R., Dona, J.Y., Linsuke, S., Madinga, J., Luz, R.I., Geeetruydan, J.V. and Lutumba, P.(2014). Malaria, schistosomiasis and soil transmitted helminth burden and their correlation with anemia in children attending primary schools in Kinshasa, Democratic Republic of Congo. PLOS ONE,9(11):1-11.

Mwatha J. K, F. M. Jones, G. Mohamed et al. (2003). “Associations between anti–Schistosoma mansoni and anti–Plasmodium falciparum antibody responses and hepatosplenomegaly, in Kenyan schoolchildren,” The Journal of Infectious Diseases,4 ( 8): 1337–1341.

Ngui R, Ishak S, Chuen C.S, Mahmud R, Lim YAL. Prevalence and Risk Factors of Intestinal Parasitism in Rural and Remote West Malaysia. PLoS Negl Trop Dis.5 (3): e974.

Njunda A.L., Assob N.J.C., Nsagha S.D, Kamga F.H.L, Mokenyu M.D. and Kwenti E.T. (2013). Comparison of capillary and venous blood using blood film microscopy in the detection of malaria parasites: A hospital based study. Scientific Journal of Microbiology. 2(5):89–94.

Njunda, A.L., Fon, S.G., Asson, N.J.C. Nsugha, D.S. Kwenti, T.D.B. and Kwenti, TE.(2015). Coinfection with malaria and intestinal parasites and it's association with anaemia in children in Cameroon. Infectious Diseases of Poverty,4(43):1-7.

Odoemene, S.N., Oluwole, A.S., Mogaji, H.O., Adegbola, M.V., Omitola, O.O., Bayegun A.A., Ojo, D.A., Sam-Wobo, S.O. and Ekpo, UF.(2020). Polyparasitism with malaria and intestinal parasite infections among infants and preschool children in Egbedore, Osun state, Nigeria. Journal of Parasitology Research, 8810148:1-8.

Sagin D. M., Mohamed G., Ismail J. J., Jok L. H., Lim J. Pui N. (2002). Intestinal parasitic infection among five interior communities at upper Rejang River, Sarawak, Malaysia, Southeast Asian Journal of Tropical Medicine and Public Health, vol. 33(1): 1820-1822.

Sarkingobir, Y., Umar, A.I., . Waheed, S.A., Miya, Y.Y., Livinus, R., Sahabi, M. and Salah, N.M. (2023). Analysis of heavy metals content in well water and it's predictive insights for students wellbeing in Almajiri Schools, Sokoto East, Nigeria. International Journal of Research in STEM Education (IJRSE),5(1):17-28

Sokhna C, Le Hesran JY, Mbaye PA, Akiana J, Camara P, Diop M, et al. (2004). Increased malaria attacks among children presenting concomitant infections by S. mansoni in Senegal. Malar J.3:43.

Sumbele I.U.N, Kimbi H.K., Ndamukong-Nyanga J.L., Nweboh M, AnchangKimbi J.K., Lum E, et al. (2015). Malarial Anaemia and Anaemia Severity in Apparently Healthy Primary School Children in Urban and Rural Settings in the Mount Cameroon Area: Cross Sectional Survey. PLoS One.10(4): e0123549.

Sunday, E.S., Temitope, M.K., Erika, N., Nature, S.A., Joseph, O., Ifeyinwa, N.C., and Onize IR.(2022). Intestinal and malaria parasitic infections among school-aged children in selected communities in Nasarawa state, Nigeria. Journal of Infectious Diseases and Preventive Medicine,10(2),1-7.

Tshikuka, J.G., Scott M.E., Gray-Donald K., and Kalumba, O.N (1996). Multiple infection with plasmodium and helminths in communities of low and relatively high socio-economic status. Annals of Tropical Medicine and Parasitology. 90:277–93.

Umar, AI., Sarkingobir, Y., and Tukur, M. (2024). Quantification of iodine in salt, foods; and determination of knowledge and pattern of consumption of iodine containing food materials in Sokoto State, Nigeria. Kalasin University Journal of Science Technology and Innovation, 3 (1): 1-15.

WHO, Fighting disease, fostering development. The World Health Report, World Health Organization, Geneva, 1996.

Wu, Davina; et al. (8 April 2011). "Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis" (PDF). Science. 332 (6026): 243–247.

Zeukeng, F, Tchinda, V.H.M, Bigoga, J.D, Ndzi, C.H.T.E.S, Abonweh, G., Makoge, V., et al. (2014). Co-infections of Malaria and Geohelminthiasis in Two Rural Communities of Nkassomo and Vian in the Mfou Health District, Cameroon. PLoS Negl Trop Dis.8(10): e3236.




DOI: http://dx.doi.org/10.62870/jocse.v3i2.27416

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